Dec 02 - 2022
BiophysXmas 2022
On the 2nd of December, the Elf and Johansson labs hosted their yearly Christmas event, BiophysXmas. Celebrating the return to in-person meetings, we gathered in the beautiful UU main building. Still, having speakers online makes the threshold lower for invited speakers, and we had the pleasure of listning to seminars from Ethan Garner and Stefan Upphoff on link.
Nov 23 - 2022
Structural flexibility explains efficient search process
With our coarse-grained molecular model of different conformation of the lac repressor, we demonstrate how disordered regions assist both rapid exploration of the DNA and recognition of the specific site. This conformational agility explains how DNA-targeting proteins can be both fast and accurate.
Oct 20 - 2022
The right drug for the right bug
We have developed a method to identify harmful bacteria and suggest an effective antibiotic treatment within hours of sampling the patient. If this type of method is made available in the clinic, patients with complex bacterial infections would be all but guaranteed an effective treatment, and physicians could make better use of the last-resort drugs, in the long run slowing the progression of resistance development.
Aug 20 - 2022
Kick-off fall 2022 in Öregrund
The Elf group kicks off the fall together with the Johansson and Jones labs in the beautiful Öregrund archipelago. This time the focus was on our brilliant staff scientists.
Jul 06 - 2022
Loremaster elected EMBO
The European Molecular Biology Organisation, not the bounty hunter, sorry...
Jan 27 - 2022
Binding long or often - the secret of fast TF search
In a study that we recently published in Science, we show how DNA-binding proteins can slide on the DNA sequence in search of their targets without getting held up unnecessarily on unspecific DNA. The result explains how LacI and other transcription factors can be both accurate and fast when turning on and off their target genes.
Dec 11 - 2021
Happy holidays!
Let's bring the year 2021 to a happy conclusion. Send some love to your friends and family and make some time for well-deserved rest; maybe it's time to brush up on your knitting...
Sep 01 - 2021
When you are blindfolded, it is easier to find a rope than a ball!
In a recent publication in Nature, we show how RecA filaments reduce the dimensionality of homologous recombination search from 3D to 2D, considerably speeding up the DNA repair process.
Oct 02 - 2020
Open Science at Krusenberg
The MSB program learns about open science and enjoys the autumn in the orchard of Krusenberg
Sep 07 - 2020
Finding your sister - a search of life and death
Arvid Gynnå defends his thesis entiteled Bacterial DNA repair and molecular search.