Our quest is to bridge the gap between quantitative physical models and biological observations in order to identify and resolve inconsistencies in our current understanding of life at the molecular level.
Oct 18 - 2018
The Elf and Johansson labs rehearsed their team working skills at one of Stockholm Escape room facilities. After an hour (or less in some cases) of intense brain activity, the teams relaxed at the rooftop bar of the Scandic hotel. Quite a pleasant outing altogether!
Sep 13 - 2018
Single Molecule Kinetics in Living Cells - A Review
In a recent review we illuminate the particular advantages of single-molecule techniques when studying kinetics in living cells and discuss solutions to specific challenges associated with these methods.
Jul 12 - 2018
Better Analysis of Noisy Multistate Diffusion Trajectories
In a recent publication we report a new algorithms for hidden Markov-based analysis of single particle tracking data, which incorporate most sources of experimental noise, including heterogeneous localization errors and missing positions.
May 21 - 2018
New analysis pipeline put to the test
Our new single molecule tracking and analysis pipeline is used for the first time in collaboration with the Johansson lab.
Apr 16 - 2018
Searching the genome
New animation illustrating the different mechanism by which LacI and Cas9 search the genome.
Dec 18 - 2017
Time-laps Christmas tree - Winner of the 2018 Elflab Christmas Image Award.
Oct 16 - 2017
The DuMPLING has arrived!
New technique to analyze dynamic phenotypes in large genetic libraries and subsequently recover the underlying genotype - all in one microfluidic chip.