We are currently looking for postdoctoral researchers for several projects, and we will also recruit an optics engineer. The on-line application for these positions will open in a few days, so please stay tuned for these exciting opportunities! In the meantime, you can find descriptions below.

Sequence-specific target localization in the living cell

We are looking for a motivated postdoc to engage in an interdisciplinary collaboration of researchers in biology, engineering, and physics http://elflab.icm.uu.se/kaw/agile.

You will use and develop new single-molecule/single-cell tools that make it possible to connect changes in the genomic DNA sequence to differences in intracellular kinetics for thousands of different bacterial strains in parallel. You will construct and phenotype large genetic libraries with respect to complex dynamic intercellular processes. The project aims at understanding the principles for sequence-specific target localization in the intracellular environment.

You will run the project independently, and although you will have much freedom to test your own ideas and hypothesis within the framework of the research plan, we encourage you to take advantage of the ample expertise that exists in the group.

We are looking for someone who has a genuine passion for quantitative microbiology and for the biophysical principles that characterize living beings. You have a PhD in microbiology, biophysics, or in another related area, which the employer considers as equivalent. You have a self-motivated personality with a keen interest in fundamental science. You have documented experience in solving scientific problems. Since the position is located in an international environment, excellent knowledge of English, both orally and in writing, is a must. Great emphasis will be placed on personal qualities such as excellent collaboration skills, as we expect you to share your knowledge with other team members. Good programming skills, good knowledge in microbiology, experience with biophysical methods development, and experience with bacterial strain construction are meriting.

Apply here


Optics engineer

We are looking for an engineer who wants to develop, build, and use advanced optical measurement methods to study biophysics and intracellular kinetics with high spatial and temporal resolution. The focus is on the development and implementation of optical techniques, for example, the MINFLUX system, to be able to follow individual molecules on the µ-second timescale in three dimensions.

We offer a stimulating interdisciplinary environment where you will work with experts in microfluidics, biophysics, image analysis, artificial intelligence, microbiology, biochemistry, and molecular biology. Our overall mission is to assemble the scientific puzzle that describes the central aspects of life at the molecular level.

You will develop microscopy methods in the rapidly growing field of detection and tracking of individual molecules in living cells and should, therefore, be familiar with the latest optical technologies in Life Science and the physics behind them. You will be responsible for the design and implementation of the microscopes, and you will support and guide other researchers in the group who use optical technologies in their research.

Apply here

Qualifications:

  • Master, or PhD in some relevant subject area, e.g., experimental physics, electrical engineering, or biophysics.
  • Experience in designing and building optical measurement systems.
  • Experience of LabView and MATLAB.
  • Experience in electronics and hardware integration.
  • Self-motivated personality with interest in basic research.
  • Excellent knowledge of English.
  • It is also favorable if you have previous experience in biophysical measurement methods, such as smFRET, FCS, and Single-Molecule Tracking (SMT), skills in FPGA programming and proficiency in CAD and instrument development.

Pushing the limits for single-molecule tracking in living cells

We are looking for a researcher who wants to develop, build, and use advanced optical methods to study biophysics and intracellular kinetics with high spatial and temporal resolution. The focus is on developing and implementing innovative optical techniques, such as the MINFLUX system, to be able to follow individual molecules on the µ-second scale.

We offer a stimulating multidisciplinary environment where you will work closely with experts in biophysics, programming, microbiology, biochemistry, and molecular biology. Our overall mission is to assemble the scientific puzzle that describes the central aspects of life at the molecular level.

You will work with optical development within the rapidly growing field of science that deals with the detection and tracking of individual molecules in living cells and should, therefore, be familiar with the latest optical methods in Life Science and the physics behind them.

Qualifications:

  • Documented experience in designing and building advanced optical systems.
  • PhD in a relevant subject area, e.g., experimental physics, electrical engineering, or biophysics.
  • Experience of FPGA programming and LabView.
  • Experience in electrical engineering and hardware integration.
  • Knowledge of the biophysics of individual molecules, such as smFRET, lifetime measurements, or rotational spectroscopy.
  • Self-motivated personality with interest in basic research.
  • Excellent knowledge of English.