Johan Elf gets new money from the Knut & Alice Wallenberg Foundation to study bacterial replication and chromosome structure

We use the DuMPLING technique for dynamic phenotyping of large genetic libraries to investigate the E. Coli cell cycle. The story was recently published in Nature Methods.

A science publication does not always describe the whole story behind the study. If you want to know how the DuMPLING really came to be, read what Micheal Lawson writes in - behind the paper; the story of how our search for optimal noise suppression led to the development of the first assay for dynamic phenotypic screening of genetic libraries.

Swedish national television visit the Elf lab to talk about how to fight antibiotic resistance.

We welcome Magnus and his group back to the program of Molecular Systems Biology (MSB)

In a recent review we illuminate the particular advantages of single-molecule techniques when studying kinetics in living cells and discuss solutions to specific challenges associated with these methods.

In a recent publication we report a new algorithms for hidden Markov-based analysis of single particle tracking data, which incorporate most sources of experimental noise, including heterogeneous localization errors and missing positions.

Our new single molecule tracking and analysis pipeline is used for the first time in collaboration with the Johansson lab.

New animation illustrating the different mechanism by which LacI and Cas9 search the genome.

Time-laps Christmas tree - Winner of the 2018 Elflab Christmas Image Award.