Oct 20 - 2022
The right drug for the right bug
We have developed a method to identify harmful bacteria and suggest an effective antibiotic treatment within hours of sampling the patient. If this type of method is made available in the clinic, patients with complex bacterial infections would be all but guaranteed an effective treatment, and physicians could make better use of the last-resort drugs, in the long run slowing the progression of resistance development.
Aug 20 - 2022
Kick-off fall 2022 in Öregrund
The Elf group kicks off the fall together with the Johansson and Jones labs in the beautiful Öregrund archipelago. This time the focus was on our brilliant staff scientists.
Jul 06 - 2022
Loremaster elected EMBO
The European Molecular Biology Organisation, not the bounty hunter, sorry...
Jan 27 - 2022
Binding long or often - the secret of fast TF search
In a study that we recently published in Science, we show how DNA-binding proteins can slide on the DNA sequence in search of their targets without getting held up unnecessarily on unspecific DNA. The result explains how LacI and other transcription factors can be both accurate and fast when turning on and off their target genes.
Dec 11 - 2021
Happy holidays!
Let's bring the year 2021 to a happy conclusion. Send some love to your friends and family and make some time for well-deserved rest; maybe it's time to brush up on your knitting...
Sep 01 - 2021
When you are blindfolded, it is easier to find a rope than a ball!
In a recent publication in Nature, we show how RecA filaments reduce the dimensionality of homologous recombination search from 3D to 2D, considerably speeding up the DNA repair process.
Oct 02 - 2020
Open Science at Krusenberg
The MSB program learns about open science and enjoys the autumn in the orchard of Krusenberg
Sep 07 - 2020
Finding your sister - a search of life and death
Arvid Gynnå defends his thesis entiteled Bacterial DNA repair and molecular search.
Jun 24 - 2020
Hit and miss for sloppy transcription factors
In a recent publication in Nature, we show how transcription factors are trading accuracy for speed when scanning the DNA. Although the transcription factor will frequently miss the target site, it will revisit the sequence enough times to ensure rapid binding
Jun 10 - 2020
Elf lab part of new research center to promote global health
Antibiotic resistance is a global health problem caused by the use and misuse of these drugs. The problem is exacerbated by the lack of new antibiotics and rapid diagnostic methods to identify the bacterial agents and their antibiotic susceptibility. In this project, we will develop diagnostic tools that will prolong the lifespan of existing and future antibiotics by allowing us to use them rationally—i.e. only for bacterial infections and when the bacterium is susceptible.